欧盟认证百奥明FUMzyme®(烟曲霉毒素降解酶)的生物转化降解功

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BIOMIN announces the EU authorization of FUMzyme® as “substances forreduction of the contamination of feed by mycotoxins”.

百奥明宣布FUMzyme®(烟曲霉毒素降解酶)作为“降低饲料中霉菌毒素污染危害的物质”已得到欧盟认证！

FUMzyme®, part of the well-established Mycofix® product line of BIOMIN, is the first-ever purified enzyme authorizedby the EU proven to biotransform fumonisins into non-toxic metabolites.

FUMzyme®是百奥明霉菌毒素脱毒剂产品系列中的一个组成部分，是首个得到欧盟认证的能够将烟曲霉毒素通过生物转化降解为无毒代谢产物的纯化的酶。

FUMzyme® was originally isolated from the fumonisin degrading soil bacteria Sphingopyxissp. MTA 144 and identified as fumonisin esterase by the BIOMIN Research Center.

FUMzyme®最初是由百奥明研究中心从能降解烟曲霉毒素的土壤细菌Sphingopyxissp. MTA 144中分离得到的，并进而鉴定出其降解烟曲霉毒素的酯酶。

The product is effective in degrading fumonisins to compounds of significantlylower toxicity in the gastrointestinal tract of animals. The sphinganine/sphingosineratio, considered the most sensitive endpoint for fumonisin toxicosis, was included as an important parameter in several short- and long-term feedingstudies conducted with pigs.

这个产品在动物的胃肠道中有效地将烟曲霉毒素降解为毒性显著降低的化合物。二羟鞘氨醇/鞘氨醇的比例被认为是烟曲霉毒素毒性反应的最为敏感的最终指标，猪上的几个短期和长期饲养实验研究中也将该比例作为重要指标。

Thesetrials consistently demonstrated that the addition of FUMzyme®significantly reduced the sphinganine/sphingosine ratio of pigs fed fumonisin-contaminateddiets. Sphinganine/sphingosine values generally returned to levels seen inanimals fed corresponding diets free from fumonisins.

这些试验的结果一致地表明：

添加FUMzyme®对饲喂了烟曲霉毒素污染的饲料的猪，能显著降低其二羟鞘氨醇/鞘氨醇比例。该数值通常会恢复到未摄食烟曲霉毒素饲料的正常动物的水平。

Untilnow, the binding of fumonisins to adsorptive substances was the only solution availableto counter fumonisin intoxication. Due to the molecular structure of these mycotoxinsand pH dependence of the reaction, fumonisins are only insufficiently adsorbed bymycotoxin-binding products in the gastrointestinal tract.

迄今为止，吸附剂是对烟曲霉毒素进行脱毒的唯一可用的解决方案。由于这类霉菌毒素的分子结构和吸附反应中对pH值的依赖性，烟曲霉毒素在胃肠道中不能被霉菌毒素吸附剂完全吸附。

Accordingto current BIOMIN Mycotoxin Survey results of 2014 in which more than 3,500 samples worldwide were analyzed, fumonisins were found in 82% of all corn samples with an average contamination of over 2,200 ppb.

根据目前百奥明2014年的霉菌毒素调查结果，已分析了来自全世界的3500个样品，其中在全部的玉米样品中82%的玉米检出有烟曲霉毒素，其平均污染水平超过2200ppb。

In 2013, BIOMIN became the first company to receive the European Commission authorizationfor feed additives with mycotoxin-counteracting properties. The authorizations werefor the deoxynivalenol-biotransforming product Biomin® BBSH 797 and theaflatoxin-binding bentonite Mycofix® Secure.

2013年，百奥明是第一家得到欧盟官方认证的公司，认可其饲料添加剂具有处理霉菌毒素的特性。该认证包括对呕吐毒素生物降解的产品百奥明BBSH797以及蒙脱石黄曲霉毒素吸附剂Mycofix®Secure。

FUMzyme®, the result of years ofintensive research at the BIOMIN Research Center in Austria, exemplifies the innovation lead of BIOMIN in developing revolutionary strategies to counteract mycotoxins.

FUMzyme®是奥地利百奥明研究中心历时多年的大量研究的结晶，也代表了百奥明在霉菌毒素处理领域不断研发革命性的解决策略而取得的创新和引领。

                                               百奥明研发总部

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